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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with conventional cardiac danger factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, doubtless secondary to high-dose testosterone. The affected person underwent profitable percutaneous intervention of the best coronary artery. Physicians and patients ought to pay attention to the medical penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).

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Polycythaemia as a complication of transdermal testosterone therapy. Relationship between endogenous intercourse hormone levels, lipoproteins and coronary atherosclerosis in men undergoing coronary angiography. Basaria S, Dobs AS. Risks versus benefits of testosterone remedy in aged males. Before sharing sensitive info, ensure you’re on a federal government site. I really have been nervous about my child’s progress since she was in fifth grade. She has at all times had challenges with reading and has not learn on grade stage for some time.

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Moreover, a part of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity. However, testosterone in physiologic doses might even be beneficial in sufferers with angina , have greater ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood move in men with established coronary artery illness . Therefore, an interaction of endogenous elements of the patient’s danger profile as nicely as the testosterone dosing may be issues of whether or not opposed occasions happen.

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